Leif Bergsagel, P.: search on Z-Library

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1

Where We Were, Where We Are, Where We Are Going: Progress in Multiple Myeloma

Bergsagel, P. Leif

Journal:

American Society of Clinical Oncology Educational Book

Year:

2014

File:

PDF, 82 KB

2014

2

Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

Chesi, Marta, Nardini, Elena, Brents, Leslie A., Schröck, Evelin, Ried, Thomas, Kuehl, W. Michael, Bergsagel, P. Leif

Journal:

Nature Genetics

Year:

1997

File:

PDF, 592 KB

1997

3

Sequence and expression of murine cDNAs encoding Xlr3a and Xlr3b, defining a new X-linked lymphocyte-regulated Xlr gene subfamily

P.Leif Bergsagel, Cynthia R. Timblin, Christine A. Kozak, W.Michael Kuehl

Journal:

Year:

1994

Language:

english

File:

PDF, 1.01 MB

english, 1994

4

The enigma of ectopic expression of FGFR3 in multiple myeloma: a critical initiating event or just a target for mutational activation during tumor progression

Chesi, Marta, Bergsagel, P. Leif, Kuehl, W. Michael

Journal:

Current Opinion in Hematology

Year:

2002

Language:

english

File:

PDF, 354 KB

english, 2002

5

Importin-β and exportin-5 are strong biomarkers of productive reoviral infection of cancer cells

Nuovo, Gerard, Tran, Hue, Gutierrez, Andres, Fadda, Paolo, Pichiorri, Flavia, Caserta, Enrico, Hofmeister, Craig C., Chesi, Marta, Leif Bergsagel, P., Morris, Don, Shi, Qiao, Coffey, Matt, Thirukkumar

Journal:

Annals of Diagnostic Pathology

Year:

2017

Language:

english

File:

PDF, 1.21 MB

english, 2017

6

FGFR3 Activates RSK2 to Mediate Hematopoietic Transformation through Tyrosine Phosphorylation of RSK2 and Activation of the MEK/ERK Pathway

Sumin Kang, Shaozhong Dong, Ting-Lei Gu, Ailan Guo, Michael S. Cohen, Sagar Lonial, Hanna Jean Khoury, Doriano Fabbro, D. Gary Gilliland, P. Leif Bergsagel, Jack Taunton, Roberto D. Polakiewicz, Jing

Journal:

Year:

2007

Language:

english

File:

PDF, 1.36 MB

english, 2007

7

Long-term results of the phase II trial of the oral mTOR inhibitor everolimus (RAD001) in relapsed or refractory Waldenstrom Macroglobulinemia

Ghobrial, Irene M., Witzig, Thomas E., Gertz, Morie, LaPlant, Betsy, Hayman, Suzanne, Camoriano, John, Lacy, Martha, Bergsagel, P. Leif, Chuma, Stacey, DeAngelo, Daniel, Treon, Steven P.

Journal:

American Journal of Hematology

Year:

2014

Language:

english

File:

PDF, 471 KB

english, 2014

8

Multiple myeloma: evolving genetic events and host interactions

Kuehl, W. Michael, Bergsagel, P. Leif

Journal:

Nature Reviews Cancer

Year:

2002

Language:

english

File:

PDF, 1.13 MB

english, 2002

9

Phase Ib/II trial of CYKLONE (cyclophosphamide, carfilzomib, thalidomide and dexamethasone) for newly diagnosed myeloma

Mikhael, Joseph R., Reeder, Craig B., Libby, Edward N., Costa, Luciano J., Bergsagel, P. Leif, Buadi, Francis, Mayo, Angela, Nagi Reddy, Sravan K., Gano, Katherine, Dueck, Amylou C., Stewart, A. Keith

Journal:

British Journal of Haematology

Year:

2015

Language:

english

File:

PDF, 283 KB

english, 2015

10

Multiple myeloma cells’ capacity to decompose H 2 O 2 determines lenalidomide sensitivity

Sebastian, Sinto, Zhu, Yuan X., Braggio, Esteban, Shi, Chang-Xin, Panchabhai, Sonali C., Van Wier, Scott A., Ahmann, Greg J., Chesi, Marta, Bergsagel, P. Leif, Stewart, A. Keith, Fonseca, Rafael

Journal:

Year:

2017

Language:

english

File:

PDF, 3.69 MB

english, 2017

11

Mate pair sequencing outperforms fluorescence in situ hybridization and improves diagnostic yield in the genomic characterization of multiple myeloma

Baughn, Linda, James, Smadbeck, Kathryn, Pearce, Pitel, Beth, Timm, Michael, Bergsagel, Leif, Jevremovic, Dragan, Shi, Min, Stewart, Keith, Braggio, Esteban, Riggs, Daniel, George, Vasmatzis, Kearney,

Journal:

Clinical Lymphoma Myeloma and Leukemia

Year:

2019

File:

PDF, 60 KB

2019

12

Identification of lenalidomide resistance pathways in myeloma and targeted resensitization using cereblon replacement, inhibition of STAT3 or targeting of IRF4

Zhu, Yuan Xiao, Shi, Chang-Xin, Bruins, Laura A., Wang, Xuewei, Riggs, Daniel L., Porter, Brooke, Ahmann, Jonathan M., de Campos, Cecilia Bonolo, Braggio, Esteban, Bergsagel, P. Leif, Stewart, A. Keit

Journal:

Blood Cancer Journal

Year:

2019

File:

PDF, 2.61 MB

2019

13

Therapy for Relapsed Multiple Myeloma

Dingli, David, Ailawadhi, Sikander, Bergsagel, P. Leif, Buadi, Francis K., Dispenzieri, Angela, Fonseca, Rafael, Gertz, Morie A., Gonsalves, Wilson I., Hayman, Susan R., Kapoor, Prashant, Kourelis, Ta

Journal:

Mayo Clinic Proceedings

Year:

2017

Language:

english

File:

PDF, 750 KB

english, 2017

14

Molecular Mechanisms of Bortezomib Resistant Adenocarcinoma Cells

Suzuki, Erika, Demo, Susan, Deu, Edgar, Keats, Jonathan, Arastu-Kapur, Shirin, Bergsagel, P. Leif, Bennett, Mark K., Kirk, Christopher J., Tridandapani, Susheela

Journal:

Year:

2011

Language:

english

File:

PDF, 360 KB

english, 2011

15

Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process

Hallek, Michael, Leif Bergsagel, P., Anderson, Kenneth C.

Journal:

Year:

1998

File:

PDF, 865 KB

1998

16

Dynamic CD138 surface expression regulates switch between myeloma growth and dissemination

Akhmetzyanova, Ilseyar, McCarron, Mark J., Parekh, Samir, Chesi, Marta, Bergsagel, P. Leif, Fooksman, David R.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.88 MB

english, 2019

17

The PI3K inhibitor GDC-0941 combines with existing clinical regimens for superior activity in multiple myeloma

Munugalavadla, V, Mariathasan, S, Slaga, D, Du, C, Berry, L, Del Rosario, G, Yan, Y, Boe, M, Sun, L, Friedman, L S, Chesi, M, Leif Bergsagel, P, Ebens, A

Journal:

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

18

Frequent occurrence of large duplications at reciprocal genomic rearrangement breakpoints in multiple myeloma and other tumors

Demchenko, Yulia, Roschke, Anna, Chen, Wei-Dong, Asmann, Yan, Bergsagel, Peter Leif, Kuehl, Walter Michael

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 2.91 MB

english, 2016

19

Frequent Dysregulation of the c-maf Proto-Oncogene at 16q23 by Translocation to an Ig Locus in Multiple Myeloma

Chesi, Marta, Bergsagel, P. Leif, Shonukan, Oluwatoyin O., Martelli, Maria Luisa, Brents, Leslie A., Chen, Theresa, SchroÌck, Evelin, Ried, Thomas, Kuehl, W. Michael

Journal:

Year:

1998

File:

PDF, 336 KB

1998

20

Comprehensive Identification of Somatic Mutations in Chronic Lymphocytic Leukemia

P. Leif Bergsagel, W. Michael Kuehl

Journal:

Year:

2011

Language:

english

File:

PDF, 93 KB

english, 2011

21

Chromosome translocations in multiple myeloma

Bergsagel, P Leif, Kuehl, W Michael

Journal:

Year:

2001

Language:

english

File:

PDF, 280 KB

english, 2001

22

Epigenetics and MicroRNAs Combine to Modulate the MDM2/p53 Axis in Myeloma

Marta Chesi, P. Leif Bergsagel

Journal:

Year:

2010

Language:

english

File:

PDF, 101 KB

english, 2010

23

V. Molecular classification and risk stratification of myeloma

Bergsagel, P. Leif, Chesi, Marta

Journal:

Hematological Oncology

Year:

2013

Language:

english

File:

PDF, 166 KB

english, 2013

24

Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma

Elaine M Hurt, Adrian Wiestner, Andreas Rosenwald, A.L Shaffer, Elias Campo, Tom Grogan, P.Leif Bergsagel, W.Michael Kuehl, Louis M Staudt

Journal:

Year:

2004

Language:

english

File:

PDF, 606 KB

english, 2004

25

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

Pei, Huadong, Zhang, Lindsey, Luo, Kuntian, Qin, Yuxin, Chesi, Marta, Fei, Frances, Bergsagel, P. Leif, Wang, Liewei, You, Zhongsheng, Lou, Zhenkun

Journal:

Year:

2011

Language:

english

File:

PDF, 707 KB

english, 2011

26

Individualizing Therapy Using Molecular Markers in Multiple Myeloma

Bergsagel, P. Leif

Journal:

Clinical Lymphoma & Myeloma

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

27

Long-term follow-up of a phase 2 trial of single agent lenalidomide in previously untreated patients with chronic lymphocytic leukaemia

Chen, Christine I., Paul, Harminder, Wang, Trina, Le, Lisa W., Dave, Nimisha, Kukreti, Vishal, Nong Wei, Ellen, Lau, Anthea, Bergsagel, Peter Leif, Trudel, Suzanne

Journal:

British Journal of Haematology

Year:

2014

Language:

english

File:

PDF, 141 KB

english, 2014

28

Critical roles for immunoglobulin translocations and cyclin D dysregulation in multiple myeloma

P. Leif Bergsagel, W. Michael Kuehl

Journal:

Immunological Reviews

Year:

2003

Language:

english

File:

PDF, 150 KB

english, 2003

29

Phase Ib/II trial of CYKLONE (cyclophosphamide, carfilzomib, thalidomide and dexamethasone) for newly diagnosed myeloma

Mikhael, Joseph R., Reeder, Craig B., Libby, Edward N., Costa, Luciano J., Bergsagel, P. Leif, Buadi, Francis, Mayo, Angela, Nagi Reddy, Sravan K., Gano, Katherine, Dueck, Amylou C., Stewart, A. Keith

Journal:

British Journal of Haematology

Year:

2015

File:

PDF, 283 KB

2015

30

Induction of Ectopie Myc Target Gene JAG2 Augments Hypoxic Growth and Tumorigenesis in a Human B-Cell Model

Jason T. Yustein, Yen-Chun Liu, Ping Gao, Chunfa Jie, Anne Le, Milena Vuka-Ross, Wee Joo Chng, Charles G. Eberhart, P. Leif Bergsagel, Chi V. Dang and Robert N. Eisenman

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.47 MB

english, 2010

31

Prediction of immunomodulatory drugs (IMiDs) sensitivity in myeloma via determination of baseline anti-oxidative stress capacity

Mountjoy, Luke, Sebastian, Sinto, Jain, Tania, Hilal, Talal, Gonzalez-Velez, Miguel, Girardo, Marlene, Ahmann, Greg, Larsen, Jeremy, Bergsagel, Leif, Fonseca, Rafael

Journal:

Year:

2020

File:

PDF, 665 KB

2020

32

Osteopontin dysregulation and lytic bone lesions in multiple myeloma

Davide F. Robbiani, Kaity Colon, Sarah Ely, Scott Ely, Marta Chesi, P. Leif Bergsagel

Journal:

Hematological Oncology

Year:

2007

Language:

english

File:

PDF, 258 KB

english, 2007

33

Complex IGH rearrangements in multiple myeloma: Frequent detection discrepancies among three different probe sets

Kim, Gina Y., Gabrea, Ana, Demchenko, Yulia N., Bergsagel, Leif, Roschke, Anna V., Kuehl, W. Michael

Journal:

Genes, Chromosomes and Cancer

Year:

2014

Language:

english

File:

PDF, 243 KB

english, 2014

34

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia

Boyiadzis, Michael, Bishop, Michael R., Abonour, Rafat, Anderson, Kenneth C., Ansell, Stephen M., Avigan, David, Barbarotta, Lisa, Barrett, Austin John, Van Besien, Koen, Bergsagel, P. Leif, Borrello,

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2016

Language:

english

File:

PDF, 909 KB

english, 2016

35

The t(4;14) Translocation in Myeloma Dysregulates Both FGFR3and a Novel Gene, MMSET, Resulting in IgH/MMSET Hybrid Transcripts

Chesi, Marta, Nardini, Elena, Lim, Robert S.C., Smith, Kerrington D., Kuehl, W. Michael, Bergsagel, P. Leif

Journal:

Year:

1998

File:

PDF, 637 KB

1998

36

Targeting NF-κB Signaling in Multiple Myeloma

Bergsagel, P. Leif, Keats, J. Jonathan, Chesi, Marta, Kuehl, W. Michael

Journal:

Clinical Lymphoma & Myeloma

Year:

2009

Language:

english

File:

PDF, 92 KB

english, 2009

37

Bone Lesions in Molecular Subtypes of Multiple Myeloma

Robbiani, Davide F., Chesi, Marta, Bergsagel, P. Leif

Journal:

Boston Medical and Surgical Journal

Year:

2004

Language:

english

File:

PDF, 76 KB

english, 2004

38

The CCND1 c.870G risk allele is enriched in individuals of African ancestry with plasma cell dyscrasias

Baughn, Linda B., Li, Zhuo, Pearce, Kathryn, Vachon, Celine M., Polley, Mei-Yin, Keats, Jonathan, Elhaik, Eran, Baird, Michael, Therneau, Terry, Cerhan, James R., Bergsagel, P. Leif, Dispenzieri, Ange

Journal:

Blood Cancer Journal

Year:

2020

Language:

english

File:

PDF, 391 KB

english, 2020

39

Distinguishing primary and secondary translocations in multiple myeloma

Ana Gabrea, P. Leif Bergsagel, W. Michael Kuehl

Journal:

Year:

2006

Language:

english

File:

PDF, 314 KB

english, 2006

40

Combination anti-CD137 and anti-CD40 antibody therapy in murine myc-driven hematological cancers

Westwood, Jennifer A., Matthews, Geoffrey M., Shortt, Jake, Faulkner, David, Pegram, Hollie J., Duong, Connie P.M., Chesi, Marta, Bergsagel, P. Leif, Sharp, Leslie L., Huhn, Richard D., Darcy, Phillip

Journal:

Leukemia Research

Year:

2014

Language:

english

File:

PDF, 3.37 MB

english, 2014

41

Long-term survival with cyclophosphamide, bortezomib and dexamethasone induction therapy in patients with newly diagnosed multiple myeloma

Reeder, Craig B., Reece, Donna E., Kukreti, Vishal, Mikhael, Joseph R., Chen, Christine, Trudel, Suzanne, Laumann, Kristina, Vohra, Harjot, Fonseca, Rafael, Bergsagel, P. Leif, Leis, Jose F., Tiedeman

Journal:

British Journal of Haematology

Year:

2014

Language:

english

File:

PDF, 85 KB

english, 2014

42

Promiscuous mechanisms underlie the antitumor effects of thalidomide analogs

Bergsagel, P Leif, Chesi, Marta

Journal:

Nature Medicine

Year:

2016

Language:

english

File:

PDF, 873 KB

english, 2016

43

newly diagnosed multiple myeloma : Results from a phase 2 trial

Kumar, Shaji K, Lacy, Martha Q, Hayman, Suzanne R, Stewart, Keith, Francis, K, Allred, Jacob, Laumann, Kristina, Greipp, Philip R, Lust, John A, Morie, A, Zeldenrust, Steven R, Bergsagel, P Leif, Reed

Year:

2014

Language:

english

File:

PDF, 378 KB

english, 2014

44

Insertion of Excised IgH Switch Sequences Causes Overexpression of Cyclin D1 in a Myeloma Tumor Cell

Ana Gabrea, P.Leif Bergsagel, Marta Chesi, Yaping Shou, W.Michael Kuehl

Journal:

Year:

1999

Language:

english

File:

PDF, 242 KB

english, 1999

45

Promiscuous Translocations into Immunoglobulin Heavy Chain Switch Regions in Multiple Myeloma

P. Leif Bergsagel, Marta Chesi, Elena Nardini, Leslie A. Brents, Suzanne L. Kirby and W. Michael Kuehl

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.68 MB

english, 1996

46

Systolic dysfunction associated with carfilzomib use in patients with multiple myeloma

Jain, Tania, Narayanasamy, Hemalatha, Mikhael, Joseph, Reeder, Craig B., Bergsagel, P. Leif, Mayo, Angela, Stewart, A. Keith, Mookadam, Farouk, Fonseca, Rafael

Journal:

Blood Cancer Journal

Year:

2017

Language:

english

File:

PDF, 388 KB

english, 2017

47

Phase 1/2 trial of ixazomib, cyclophosphamide and dexamethasone in patients with previously untreated symptomatic multiple myeloma

Kumar, Shaji K., Buadi, Francis K., LaPlant, Betsy, Halvorson, Alese, Leung, Nelson, Kapoor, Prashant, Dingli, David, Gertz, Morie A., Go, Ronald S., Bergsagel, P. Leif, Lin, Yi, Dispenzieri, Angela,

Journal:

Blood Cancer Journal

Year:

2018

Language:

english

File:

PDF, 933 KB

english, 2018

48

Ectopic expression of fibroblast growth factor receptor 3 promotes myeloma cell proliferation and prevents apoptosis

Plowright, Elizabeth E., Li, Zhihua, Bergsagel, P. Leif, Chesi, Marta, Barber, Dwayne L., Branch, Donald R., Hawley, Robert G., Stewart, A. Keith

Journal:

Year:

2000

File:

PDF, 162 KB

2000

49

Evidence for Cytogenetic and Fluorescence In Situ Hybridization Risk Stratification of Newly Diagnosed Multiple Myeloma in the Era of Novel Therapies

Kapoor, Prashant, Fonseca, Rafael, Rajkumar, S. Vincent, Sinha, Shirshendu, Gertz, Morie A., Stewart, A. Keith, Bergsagel, P. Leif, Lacy, Martha Q., Dingli, David D., Ketterling, Rhett P.

Journal:

Mayo Clinic Proceedings

Year:

2010

Language:

english

File:

PDF, 827 KB

english, 2010

50

Do Cytogenetics Predict Likelihood to Attain Minimal Residual Disease (MRD) Post Autologous Stem Cell Transplantation (SCT) in Multiple Myeloma (MM)?

Jain, Tania, Guerrero, Carlo, Kosiorek, Heidi, Butterfield, Richard, Mountjoy, Luke, Reeder, Craig, Bergsagel, P. Leif, Larsen, Jeremy T., Stewart, Keith, Fonseca, Rafael

Journal:

Biology of Blood and Marrow Transplantation

Year:

2019

File:

PDF, 228 KB

2019

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